Measures should be taken to resolve the concerns of each side, and economic and trade issues "cannot be politicized", Xi said.
Kerry said the world is undergoing major changes and Washington considers US-China ties to be on a strategic level.
Bonnie S. Glaser, senior advisor for Asia, Freeman Chair in China Studies of Center for Strategic and International Studies, said the biggest challenge in bilateral relations is "managing differences".
If Kerry "can truly convey a genuine desire to cooperate and work with China rather than as an adversary, then he stands a chance of strengthening bilateral relations", said George Koo, international business consultant and board member of New America Media.
The talks on Saturday ended up being fruitful.
During the meeting between Li and Kerry, the two sides agreed to issue a joint statement on climate change, and announced the two countries will set up a climate change workforce, under the framework of the China-US Strategic and Economic Dialogue.
China and the United States should also conduct a dialogue on cyberspace, in a calm and objective fashion, Wang said.
Beijing and Washington have been trading accusations in recent months of massive cyber intrusions. While the US says hacking attacks from China have targeted US government and corporate computer networks, China refutes the claim and says that it is the victim of large-scale cyber attacks from the United States.
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