"We don't need an 'alliance' in any sense of that word, but we need cooperation, and it should be comprehensive."
Annual China-Russia trade grew more than 11 percent in 2012 from $88.16 billion. It is expected to hit $100 billion in 2015 and $200 billion in 2020, a target set last year.
Denisov said Russia will get better equipped to welcome more high-level investment from China, especially in its Far East region.
"Russia wants to be more active and to raise the profile of economic cooperation in East Asia. China is a natural and leading partner there," said Denisov, citing potential cooperation in the fields of energy, electricity, metal and wood processing.
Russia will continue improving its investment environment to make enterprises feel "comfortable and protected", he said.
"I especially want to support small and medium-sized businesses in the border regions.
"Nothing is fixed. We must strive to achieve good results. Russia and China must be frank with each other and help each other. This is also an objective we want to see during Xi's visit,"he said.
Rare tree blooms after 30 years