Second-placed AS Roma can cut the lead back to three points if they win at Milan late on Monday. Napoli, who also failed to progress despite winning four of their six Champions League group games and entered the Europa League, will face Swansea in the round of 32.

The Welsh opponents play in the English Premier League. "They are tough opponents," said Napoli coach Rafa Benitez, who led London team Chelsea to victory on the Europa League last season. "They've made great progress in recent years. Swansea are a team who are on the up and love passing the ball and playing well.

"Their coach (Michael) Laudrup likes possession of the ball and he gets a squad with some quality players to express themselves brilliantly". Fiorentina will take on Danish side Esbjerg and are on course to face Juve in the last 16. Rome side Lazio have been pitched against Ludogorets of Bulgaria.

On Sunday Napoli consolidated third place in Serie A and stayed in the hunt for the championship by thumping Inter 4-2 at home. Fiorentina leapfrogged Inter and moved into fourth place thanks to an impressive 3-0 win over Bologna. Juventus have 43 points from 16 games, while Roma have 37 points and a game in hand. Napoli have 35 points, Fiorentina have 30 and fifth-placed Inter have 28.