"I can't do anything without help from my parents - eating, bathing, anything," said the 34-year-old, who has muscular dystrophy. "I need to consider what it will be like when my health deteriorates and no one will take care of me.
"I want the choice of a painless ending when I am ready."
Li is an advocate of euthanasia, also called assisted suicide or mercy killing. Li said she believes that a person should be allowed to decide when, where and how their life ends, even it involves enlisting the help of a relative or health professional.
Euthanasia is illegal in China, but since 2007, Li has been campaigning for a change in legislation that would see her country follow the Netherlands, Switzerland, Belgium and some US states in allowing some form of euthanasia.
"When that day comes, I'll be able to reach my destination in peace, without fear," said Li, speaking over the phone from her home in Yinchuan, the Ningxia Hui autonomous region.